GRADUATE SCHOOL

Departments

Graduate School of Medicine/Graduate School of Public Health

Staff Information

Haruo Watanabe

MD, PhD
Affiliation Campus:Narita

Profile (Career Summary)

Former Director-General of National Institute of Infectious Diseases (NIID), Former Professor (Tokyo University, Faculty of Medicine), Honorary member of NIID, Research Supervisor (Japan Agency for Medical Research and Development), President (KUROZUMI Medical Science Promotion Foundation)

Academic Degree

PhD (MD)

Specialized Field

Infectious Diseases, Bacteriology, Molecular epidemiology

Message to Students

Enjoy the activities of researches and contribute to the development of medical science.

Research Theme

  1. Molecular mechanism of bacterial virulence; enteric pathogens and others
  2. Molecular pathogenesis of new emerging diseases; invasive group A streptococcus infections and others
  3. Molecular epidemiological analysis of infectious pathogens including EHEC,
  4. Analysis of drug resistance of food-borne pathogens by “One-Health Approach”

References

  1. Shaik S, et.al. Comparative genomic analysis of globally dominant ST131 clone with other epidemiologically successful extraintestinal pathogenic Escherichia coli (ExPEC) lineages. MBio. 24;8(5). pii: e01596-17. (2017)
  2. Tani,H., et.al. Efficacy of T-705 (Favipiravir) in the treatment of lethal severe fever with thrombocytopenia syndrome virus infection. mSphereTM. 1(1). E00061-15. (2016)
  3. Alam, M., et.al. Occurrence in Mexico, 1998–2008, of Vibrio cholera CTX+ El Tor carrying an additional truncated CTX prophage.  Pro.Natl.Acad.Sci.USA. 111(27):9917-9922. (2014)
  4. Yamamoto S, et. al.  Regulation of natural competence by the orphan two-component system sensor kinase ChiS involves a non-canonical transmembrane regulator in Vibrio cholerae. Mol. Microbiol. 91: 326-347. (2014)
  5. Morita-Ishihara T, et al. EspO1-2 regulates EspM2-mediated RhoA activity to stabilize formation of focal adhesions in enterohemorrhagic Escherichia coli - infected host cells. PLoS One. 8(2): e55960. (2013)
  6. Matsumura T, et.al. Interferon-γ-producing immature myeloid cells confer protection against severe invasive group A streptococcus infections. Nature Communication: 3:678. (DOI:10.1038/ncomms1677) (2012)