GRADUATE SCHOOL

GRADUATE SCHOOL

Departments

Graduate School of Medicine/Graduate School of Public Health

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Staff Information

Jun Kosaka

MD, PhD
Affiliation Campus：Narita

Specialized Field

Anatomy, Histology, Developmental Biology, Molecular Biology, Neuroscience, Visual Science

Message to Students

A butterfly is beautiful, and a stag beetle is so cool!…, I think so, when I was a child. Science is to study “why a butterfly is so beautiful?” using modern biological methodologies, gene manipulation, cell culture, histochemistry, electron microscopy and so on. I want young students to know “Science is interesting and enjoyable!”

Research Theme

Optic nerve regeneration after peripheral nerve graft in mammals
Cytoarchitecture of the neural retina and visual system
Rescue from CNS neuron death
Development, regeneration and morphogenesis of tissue cells

References

  1. Matsumoto, Kosaka, et al., Enhancement of lymphatic vessels in the superficial layer in a rat model of a lymphedematous response. Plastic. Reconstr. Surg.Global Open. 2018;6:e1770. doi: 10.1097/GOX.0000000000001770
  2. Suzuki, Fukumoto, et al., Comparative morphology and development of extra-ocular muscles in the lamprey and gnathostomes reveal the ancestral state and developmental patterns of the vertebrate head. Zool. Lett. 2016;2:10. doi: 10.1186/s40851-016-0046-3
  3. Komatsu, et al. Vascularized peripheral nerve grafting promotes myelination of regrowing optic nerve. Neuroreport. 2013; 24:566-571.
  4. Li, Weng, et al., Loss of Ahi1 affects early development by impairing BM88/Cend1-mediated neuronal differentiation. J. Neurosci. 2013;33:8172-8184.
  5. Wakabayashi, Kosaka, et al., C38, equivalent to BM88, is developmentally expressed in maturing retinal neurons and enhances neuronal maturation. J. Neurochem. 2010;112:1235-1248.
  6. Sekiguchi-Tonosaki, Kosaka, et al.. Acetylcholine induces Ca2+ signaling in chicken retinal pigmented epithelial cells during dedifferentiation. Am J Physiol Cell Physiol. 2009;296:C1195-1206.
  7. Kimura, Kosaka, et al. Quantification of in situ hybridization signals in rat testes. J Histochem Cytochem. 2004; 52:813-820.
  8. Quan, Kosaka, et al. Survival of axotomized retinal ganglion cells in peripheral nerve-grafted ferrets. Invest Ophthalmol Vis Sci. 1999;40:2360-2366.
  9. Kosaka, et al. Differential localization and expression of α and β isoenzymes of Protein Kinase C in the rat retina. J. Neurosci Res. 1998;54:655-663.